| 2/15 | Holy Cross | @ | Baylor | 6:35 pm | |
| 2/16 | Holy Cross | @ | Baylor DH | 1 pm | |
| 2/17 | Holy Cross | @ | Baylor | 1 pm | |
| 2/22 | Holy Cross | @ | UAB | 4 pm | |
| 2/23 | Holy Cross | @ | UAB | 1 pm | |
| 2/24 | Holy Cross | @ | UAB | 12 pm | |
| 3/2 | Holy Cross | vs. | Nicholls (Lake Charles, La.) | 1 pm | |
| 3/2 | Holy Cross | @ | McNeese | 4 pm | |
| 3/3 | Holy Cross | vs. | Nicholls (Lake Charles, La.) | 1 pm | |
| 3/4 | Holy Cross | @ | McNeese | 1 pm | |
| 3/6 | Holy Cross | @ | LSU | 6:30 pm | |
| 3/8 | Holy Cross | @ | Southern Miss | 6 pm | |
| 3/9 | Holy Cross | @ | Southern Miss | 2 pm | |
| 3/10 | Holy Cross | @ | Southern Miss | 12 pm | |
| 3/12 | Boston College | @ | Holy Cross | 3 pm | |
| 3/16 | Holy Cross | @ | Northeastern DH | 11 am | |
| 3/17 | Northeastern | @ | Holy Cross DH | 1 pm | |
| 3/19 | Massachusetts | @ | Holy Cross | 5 pm | |
| 3/20 | Holy Cross | @ | UMass Lowell | 6 pm | |
| 3/23 | * | Navy | @ | Holy Cross DH | 1 pm |
| 3/24 | * | Bucknell | @ | Holy Cross DH | 1 pm |
| 3/26 | Holy Cross | @ | Harvard | 3:30 pm | |
| 3/30 | * | Lehigh | @ | Holy Cross DH | 1 pm |
| 3/31 | * | Lehigh | @ | Holy Cross | 1 pm |
| 4/3 | Dartmouth | @ | Holy Cross | 5 pm | |
| 4/6 | * | Holy Cross | @ | Navy DH | |
| 4/7 | * | Holy Cross | @ | Navy | |
| 4/10 | Holy Cross | @ | Rhode Island | 3:30 pm | |
| 4/13 | * | Holy Cross | @ | Bucknell DH | 12 pm |
| 4/14 | * | Holy Cross | @ | Bucknell | 1 pm |
| 4/17 | * | Holy Cross | @ | Army | |
| 4/20 | * | Lafayette | @ | Holy Cross DH | 1 pm |
| 4/21 | * | Lafayette | @ | Holy Cross | 1 pm |
| 4/24 | Hartford | @ | Holy Cross | 5 pm | |
| 4/27 | * | Army | @ | Holy Cross DH | 1 pm |
| 4/28 | * | Army | @ | Holy Cross DH | 1 pm |
| 5/1 | Marist | @ | Holy Cross | 5 pm | |
| 5/4 | * | Holy Cross | @ | Lafayette DH | |
| 5/5 | * | Holy Cross | @ | Lehigh DH |
