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| 2/15 | Western Michigan | @ | Southeast Missouri | 3 pm |
| 2/16 | Western Michigan | @ | Southeast Missouri | 2 pm |
| 2/17 | Western Michigan | @ | Southeast Missouri | 12 pm |
| 2/19 | Harris-Stowe State | @ | Southeast Missouri | 3 pm |
| 2/22 | Western Illinois | @ | Southeast Missouri | 3 pm |
| 2/23 | Western Illinois | @ | Southeast Missouri | 2 pm |
| 2/24 | Western Illinois | @ | Southeast Missouri | 1 pm |
| 2/26 | Southeast Missouri | @ | Vanderbilt | 4:30 pm |
| 3/1 | Purdue Fort Wayne | @ | Southeast Missouri | 3 pm |
| 3/2 | Purdue Fort Wayne | @ | Southeast Missouri | 2 pm |
| 3/3 | Purdue Fort Wayne | @ | Southeast Missouri | 1 pm |
| 3/5 | Saint Louis | @ | Southeast Missouri | 3 pm |
| 3/6 | Southern Illinois | @ | Southeast Missouri | 3 pm |
| 3/8 | * | UT Martin | @ | Southeast Missouri | 6 pm |
| 3/9 | * | UT Martin | @ | Southeast Missouri | 2 pm |
| 3/10 | * | UT Martin | @ | Southeast Missouri | 1 pm |
| 3/12 | Illinois State | @ | Southeast Missouri | 6 pm |
| 3/13 | Southeast Missouri | @ | Southern Illinois | 3 pm |
| 3/15 | * | Southeast Missouri | @ | SIUE | 6 pm |
| 3/16 | * | Southeast Missouri | @ | SIUE | 1 pm |
| 3/17 | * | Southeast Missouri | @ | SIUE | 1 pm |
| 3/19 | Memphis | @ | Southeast Missouri | 6 pm |
| 3/22 | * | Austin Peay | @ | Southeast Missouri | 6 pm |
| 3/23 | * | Austin Peay | @ | Southeast Missouri | 2 pm |
| 3/24 | * | Austin Peay | @ | Southeast Missouri | 1 pm |
| 3/26 | Arkansas State | @ | Southeast Missouri | 6 pm |
| 3/29 | * | Southeast Missouri | @ | Eastern Illinois | 3 pm |
| 3/30 | * | Southeast Missouri | @ | Eastern Illinois | 1 pm |
| 3/31 | * | Southeast Missouri | @ | Eastern Illinois | 1 pm |
| 4/2 | Missouri State | @ | Southeast Missouri | 6 pm |
| 4/5 | * | Jacksonville State | @ | Southeast Missouri | 6 pm |
| 4/6 | * | Jacksonville State | @ | Southeast Missouri | 2 pm |
| 4/7 | * | Jacksonville State | @ | Southeast Missouri | 1 pm |
| 4/9 | Southeast Missouri | @ | Saint Louis | 6 pm |
| 4/12 | * | Southeast Missouri | @ | Murray State | 5 pm |
| 4/13 | * | Southeast Missouri | @ | Murray State | 2 pm |
| 4/14 | * | Southeast Missouri | @ | Murray State | 1 pm |
| 4/16 | Southeast Missouri | @ | Arkansas State | 6:30 pm |
| 4/18 | * | Tennessee Tech | @ | Southeast Missouri | 6 pm |
| 4/19 | * | Tennessee Tech | @ | Southeast Missouri | 6 pm |
| 4/20 | * | Tennessee Tech | @ | Southeast Missouri | 2 pm |
| 4/23 | McKendree | @ | Southeast Missouri | 6 pm |
| 4/26 | Southeast Missouri | @ | Purdue | 6 pm |
| 4/27 | Southeast Missouri | @ | Purdue | 6 pm |
| 4/28 | Southeast Missouri | @ | Purdue | 1 pm |
| 4/30 | Southeast Missouri | @ | Missouri | 6:30 pm |
| 5/3 | * | Southeast Missouri | @ | Belmont | 6 pm |
| 5/4 | * | Southeast Missouri | @ | Belmont | 6 pm |
| 5/5 | * | Southeast Missouri | @ | Belmont | 2 pm |
| 5/10 | * | Eastern Kentucky | @ | Southeast Missouri | 6 pm |
| 5/11 | * | Eastern Kentucky | @ | Southeast Missouri | 6 pm |
| 5/12 | * | Eastern Kentucky | @ | Southeast Missouri | 1 pm |
| 5/16 | * | Southeast Missouri | @ | Morehead State | 5 pm |
| 5/17 | * | Southeast Missouri | @ | Morehead State | 5 pm |
| 5/18 | * | Southeast Missouri | @ | Morehead State | 1 pm |
