| 2/18 | | Purdue | vs. | South Dakota State (Sugar Land, Texas) | 3 pm |
| 2/19 | | Purdue | vs. | South Dakota State DH (Sugar Land, Texas) | 1 pm |
| 2/20 | | Purdue | vs. | South Dakota State (Sugar Land, Texas) | 1 pm |
| 2/24 | | South Dakota State | @ | UIW | 6:30 pm |
| 2/25 | | South Dakota State | @ | UIW | 6:30 pm |
| 2/26 | | South Dakota State | @ | UIW | 1 pm |
| 3/2 | | South Dakota State | @ | Minnesota | 6 pm |
| 3/4 | | South Dakota State | @ | Central Arkansas | 6 pm |
| 3/5 | | South Dakota State | @ | Central Arkansas DH | 1 pm |
| 3/6 | | South Dakota State | @ | Central Arkansas | 1 pm |
| 3/9 | | South Dakota State | @ | Creighton | 6:30 pm |
| 3/11 | | South Dakota State | @ | Wichita State | 3 pm |
| 3/12 | | South Dakota State | @ | Wichita State | 2 pm |
| 3/13 | | South Dakota State | @ | Wichita State | 1 pm |
| 3/17 | | South Dakota State | @ | Northwestern State | |
| 3/18 | | South Dakota State | @ | Northwestern State DH | |
| 3/19 | | South Dakota State | @ | Northwestern State | |
| 3/23 | | South Dakota State | @ | Nebraska | 6:35 pm |
| 3/25 | * | South Dakota State | @ | Oral Roberts | 6 pm |
| 3/26 | * | South Dakota State | @ | Oral Roberts | 2 pm |
| 3/27 | * | South Dakota State | @ | Oral Roberts | 1 pm |
| 3/30 | | South Dakota State | @ | Creighton | 6:30 pm |
| 4/1 | * | South Dakota State | @ | St. Thomas | 3 pm |
| 4/2 | * | South Dakota State | @ | St. Thomas | 1 pm |
| 4/3 | * | South Dakota State | @ | St. Thomas | 1 pm |
| 4/5 | | Dakota Wesleyan | @ | South Dakota State | 3 pm |
| 4/8 | * | Western Illinois | @ | South Dakota State | 3 pm |
| 4/9 | * | Western Illinois | @ | South Dakota State | 1 pm |
| 4/10 | * | Western Illinois | @ | South Dakota State | 1 pm |
| 4/12 | | Northwestern (Iowa) | @ | South Dakota State | 3 pm |
| 4/15 | * | South Dakota State | @ | Northern Colorado | |
| 4/16 | * | South Dakota State | @ | Northern Colorado | |
| 4/17 | * | South Dakota State | @ | Northern Colorado | |
| 4/20 | | Briar Cliff | @ | South Dakota State | 3 pm |
| 4/26 | | South Dakota State | @ | Minnesota | 6 pm |
| 4/29 | * | North Dakota State | @ | South Dakota State | 3 pm |
| 4/30 | * | North Dakota State | @ | South Dakota State | 1 pm |
| 5/1 | * | North Dakota State | @ | South Dakota State | 1 pm |
| 5/6 | * | South Dakota State | @ | Omaha | 6 pm |
| 5/7 | * | South Dakota State | @ | Omaha | 6 pm |
| 5/8 | * | South Dakota State | @ | Omaha | 1 pm |
| 5/13 | * | St. Thomas | @ | South Dakota State | 3 pm |
| 5/14 | * | St. Thomas | @ | South Dakota State | 1 pm |
| 5/15 | * | St. Thomas | @ | South Dakota State | 1 pm |
| 5/19 | * | Oral Roberts | @ | South Dakota State | 3 pm |
| 5/20 | * | Oral Roberts | @ | South Dakota State | 1 pm |
| 5/21 | * | Oral Roberts | @ | South Dakota State | 1 pm |
