| 2/18 | | Purdue | vs. | South Dakota State (Sugar Land, Texas) | 3 pm |
| 2/19 | | Purdue | vs. | South Dakota State DH (Sugar Land, Texas) | 1 pm |
| 2/20 | | Purdue | vs. | South Dakota State (Sugar Land, Texas) | 1 pm |
| 2/25 | | Princeton | vs. | Purdue (Holly Springs, N.C.) | 3 pm |
| 2/26 | | Princeton | vs. | Purdue DH (Holly Springs, N.C.) | 1 pm |
| 2/27 | | Princeton | vs. | Purdue (Holly Springs, N.C.) | 1 pm |
| 3/2 | | Purdue | @ | Charlotte | |
| 3/4 | | Longwood | vs. | Purdue (Holly Springs, N.C.) | 3 pm |
| 3/5 | | Longwood | vs. | Purdue (Holly Springs, N.C.) | 1 pm |
| 3/6 | | Longwood | vs. | Purdue (Holly Springs, N.C.) | 1 pm |
| 3/11 | | Bellarmine | @ | Purdue | 4 pm |
| 3/12 | | Bellarmine | @ | Purdue | 1 pm |
| 3/13 | | Bellarmine | @ | Purdue | 1 pm |
| 3/15 | | Dayton | @ | Purdue | 4 pm |
| 3/17 | | Purdue | @ | Illinois State | 6 pm |
| 3/18 | | Purdue | @ | Illinois State | 3 pm |
| 3/19 | | Illinois State | @ | Purdue | 1 pm |
| 3/20 | | Illinois State | @ | Purdue | 1 pm |
| 3/22 | | Northern Illinois | @ | Purdue | 4 pm |
| 3/25 | * | Ohio State | @ | Purdue | 4 pm |
| 3/26 | * | Ohio State | @ | Purdue | 1 pm |
| 3/27 | * | Ohio State | @ | Purdue | 1 pm |
| 3/29 | | UIC | @ | Purdue | 4 pm |
| 3/30 | | Purdue | @ | Indiana State | 4 pm |
| 4/1 | * | Purdue | @ | Illinois | 6 pm |
| 4/2 | * | Purdue | @ | Illinois | 3 pm |
| 4/3 | * | Purdue | @ | Illinois | 1 pm |
| 4/6 | | Indiana State | @ | Purdue | 4 pm |
| 4/8 | * | Indiana | @ | Purdue | 4 pm |
| 4/9 | * | Indiana | @ | Purdue | 1 pm |
| 4/10 | * | Indiana | @ | Purdue | 1 pm |
| 4/12 | | IPFW | @ | Purdue | 6 pm |
| 4/14 | * | Purdue | @ | Penn State | |
| 4/15 | * | Purdue | @ | Penn State | |
| 4/16 | * | Purdue | @ | Penn State | |
| 4/19 | | Purdue | @ | UIC | 7 pm |
| 4/20 | | Evansville | @ | Purdue | 6 pm |
| 4/22 | | Belmont | @ | Purdue | 6 pm |
| 4/23 | | Belmont | @ | Purdue | 6 pm |
| 4/24 | * | Belmont | @ | Purdue | 1 pm |
| 4/26 | | Valparaiso | @ | Purdue | 6 pm |
| 4/29 | * | Michigan | @ | Purdue | 6 pm |
| 4/30 | * | Michigan | @ | Purdue | 6 pm |
| 5/1 | * | Michigan | @ | Purdue | 1 pm |
| 5/6 | * | Purdue | @ | Iowa | 6 pm |
| 5/7 | * | Purdue | @ | Iowa | 2 pm |
| 5/8 | * | Purdue | @ | Iowa | 1 pm |
| 5/10 | | Butler | @ | Purdue | 6 pm |
| 5/13 | * | Purdue | @ | Northwestern | 3:30 pm |
| 5/14 | * | Purdue | @ | Northwestern | 2 pm |
| 5/15 | * | Purdue | @ | Northwestern | 1 pm |
| 5/19 | * | Maryland | @ | Purdue | 6 pm |
| 5/20 | * | Maryland | @ | Purdue | 6 pm |
| 5/21 | * | Maryland | @ | Purdue | 1 pm |
