| 2/18 | | Illinois | vs. | Kansas (Corpus Christi, Texas) | 7 pm |
| 2/19 | | Illinois | vs. | Kansas (Corpus Christi, Texas) | 2 pm |
| 2/20 | | Illinois | vs. | Kansas (Corpus Christi, Texas) | 11 am |
| 2/25 | | Illinois | vs. | Middle Tennessee (Conway, S.C.) | |
| 2/26 | | Illinois | @ | Coastal Carolina | |
| 2/27 | | Illinois | @ | UNC Wilmington | |
| 3/4 | | Illinois | vs. | Notre Dame (US Bank Stadium, Minneapolis) | 3 pm |
| 3/5 | | Illinois | vs. | West Virginia (US Bank Stadium, Minneapolis) | 3 pm |
| 3/6 | | Illinois | vs. | Kansas (US Bank Stadium, Middeapolis) | 2 pm |
| 3/8 | | Eastern Illinois | @ | Illinois | 4 pm |
| 3/11 | | Illinois | @ | Western Kentucky | 3 pm |
| 3/12 | | Illinois | @ | Western Kentucky | 1 pm |
| 3/13 | | Illinois | @ | Western Kentucky | 1 pm |
| 3/15 | | Butler | @ | Illinois | 4 pm |
| 3/18 | | Illinois | @ | Southern Illinois | |
| 3/19 | | Illinois | @ | Southern Illinois | |
| 3/20 | | Illinois | @ | Southern Illinois | |
| 3/22 | | Bradley | @ | Illinois | |
| 3/25 | * | Illinois | @ | Michigan State | |
| 3/26 | * | Illinois | @ | Michigan State | |
| 3/27 | * | Illinois | @ | Michigan State | |
| 3/29 | | Illinois | @ | Missouri | |
| 4/1 | * | Purdue | @ | Illinois | 6 pm |
| 4/2 | * | Purdue | @ | Illinois | 3 pm |
| 4/3 | * | Purdue | @ | Illinois | 1 pm |
| 4/5 | | Illinois | @ | Illinois State | |
| 4/8 | * | Illinois | @ | Iowa | 6 pm |
| 4/9 | * | Illinois | @ | Iowa | 2 pm |
| 4/10 | * | Illinois | @ | Iowa | 1 pm |
| 4/12 | | Illinois State | @ | Illinois | 6 pm |
| 4/15 | * | Northwestern | @ | Illinois | 6 pm |
| 4/16 | * | Northwestern | @ | Illinois | 3 pm |
| 4/17 | * | Northwestern | @ | Illinois | 1 pm |
| 4/19 | | Illinois | @ | Illinois State | |
| 4/22 | * | Maryland | @ | Illinois | 6 pm |
| 4/23 | * | Maryland | @ | Illinois | 3 pm |
| 4/24 | * | Maryland | @ | Illinois | 1 pm |
| 4/27 | | Illinois | @ | Bradley | |
| 4/29 | * | Illinois | @ | Indiana | |
| 4/30 | * | Illinois | @ | Indiana | |
| 5/1 | * | Illinois | @ | Indiana | |
| 5/3 | | Illinois State | @ | Illinois | 6 pm |
| 5/6 | | Miami (Ohio) | @ | Illinois | 6 pm |
| 5/7 | | Miami (Ohio) | @ | Illinois | 3 pm |
| 5/8 | | Miami (Ohio) | @ | Illinois | 1 pm |
| 5/13 | * | Nebraska | @ | Illinois | 6 pm |
| 5/14 | * | Nebraska | @ | Illinois | 3 pm |
| 5/15 | * | Nebraska | @ | Illinois | 1 pm |
| 5/19 | * | Illinois | @ | Penn State | |
| 5/20 | * | Illinois | @ | Penn State | |
| 5/21 | * | Illinois | @ | Penn State | |
