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| 2/19 | | Missouri | @ | Grand Canyon | 4 pm |
| 2/20 | | Missouri | @ | Grand Canyon DH | 3 pm |
| 2/21 | | Missouri | @ | Grand Canyon | 1 pm |
| 2/26 | | Omaha | @ | Missouri | 3 pm |
| 2/27 | | Omaha | @ | Missouri DH | 12 pm |
| 2/28 | | Omaha | @ | Missouri | 1 pm |
| 3/4 | | Dallas Baptist | vs. | Missouri (Frisco, Texas) | 8 pm |
| 3/5 | | Dallas Baptist | vs. | Missouri (Frisco, Texas) | 6 pm |
| 3/6 | | Missouri | vs. | Oklahoma (Frisco, Texas) | 7 pm |
| 3/7 | | Arizona | vs. | Missouri (Frisco, Texas) | 12 pm |
| 3/10 | | Missouri | @ | Saint Louis | 3 pm |
| 3/12 | | Illinois State | @ | Missouri | 3 pm |
| 3/13 | | Illinois State | @ | Missouri DH | 12 pm |
| 3/14 | | Illinois State | @ | Missouri | 1 pm |
| 3/19 | * | Missouri | @ | Kentucky | |
| 3/20 | * | Missouri | @ | Kentucky | |
| 3/21 | * | Missouri | @ | Kentucky | |
| 3/25 | * | Vanderbilt | @ | Missouri | |
| 3/26 | * | Vanderbilt | @ | Missouri | 6:30 pm |
| 3/27 | * | Vanderbilt | @ | Missouri | 2 pm |
| 3/30 | | Missouri | @ | Kansas | 3 pm |
| 4/1 | * | Texas A&M | @ | Missouri | |
| 4/2 | * | Texas A&M | @ | Missouri | |
| 4/3 | * | Texas A&M | @ | Missouri | |
| 4/9 | * | Missouri | @ | South Carolina | 7 pm |
| 4/10 | * | Missouri | @ | South Carolina | 4 pm |
| 4/11 | * | Missouri | @ | South Carolina | 1:30 pm |
| 4/13 | | Missouri State | @ | Missouri | 6:30 pm |
| 4/16 | * | Missouri | @ | Florida | |
| 4/17 | * | Missouri | @ | Florida | |
| 4/18 | * | Missouri | @ | Florida | |
| 4/20 | | Missouri | @ | Missouri State | 6:30 pm |
| 4/23 | * | Georgia | @ | Missouri | 6:30 pm |
| 4/24 | * | Georgia | @ | Missouri | 2 pm |
| 4/25 | * | Georgia | @ | Missouri | 1 pm |
| 4/27 | | Missouri | @ | Kansas State | 6 pm |
| 4/30 | * | Missouri | @ | Alabama | |
| 5/1 | * | Missouri | @ | Alabama | |
| 5/2 | * | Missouri | @ | Alabama | |
| 5/7 | * | Tennessee | @ | Missouri | |
| 5/8 | * | Tennessee | @ | Missouri | |
| 5/9 | * | Tennessee | @ | Missouri | |
| 5/14 | * | Missouri | @ | Mississippi State | |
| 5/15 | * | Missouri | @ | Mississippi State | |
| 5/16 | * | Missouri | @ | Mississippi State | |
| 5/20 | * | Auburn | @ | Missouri | |
| 5/21 | * | Auburn | @ | Missouri | |
| 5/22 | * | Auburn | @ | Missouri | |
