| 2/19 | Cincinnati | @ | Clemson | 4 pm | |
| 2/20 | Cincinnati | @ | Clemson | 3 pm | |
| 2/21 | Cincinnati | @ | Clemson | 1 pm | |
| 2/26 | South Carolina | @ | Clemson | 4 pm | |
| 2/27 | Clemson | vs. | South Carolina (Greenville, S.C.) | 4 pm | |
| 2/28 | Clemson | @ | South Carolina | ||
| 3/2 | ETSU | @ | Clemson | 4 pm | |
| 3/5 | * | Notre Dame | @ | Clemson | 4 pm |
| 3/6 | * | Notre Dame | @ | Clemson | 3 pm |
| 3/7 | * | Notre Dame | @ | Clemson | 1 pm |
| 3/9 | USC Upstate | @ | Clemson | 4 pm | |
| 3/12 | * | Clemson | @ | North Carolina | |
| 3/13 | * | Clemson | @ | North Carolina | |
| 3/14 | * | Clemson | @ | North Carolina | |
| 3/16 | Georgia State | @ | Clemson | 6 pm | |
| 3/19 | * | Virginia Tech | @ | Clemson | 6 pm |
| 3/20 | * | Virginia Tech | @ | Clemson | 3 pm |
| 3/21 | * | Virginia Tech | @ | Clemson | 1 pm |
| 3/23 | Clemson | vs. | Georgia Southern (Augusta, Ga.) | ||
| 3/26 | * | Clemson | @ | Boston College | |
| 3/27 | * | Clemson | @ | Boston College | |
| 3/28 | * | Clemson | @ | Boston College | |
| 3/30 | Georgia | @ | Clemson | 6 pm | |
| 4/2 | * | Clemson | @ | NC State | |
| 4/3 | * | Clemson | @ | NC State | |
| 4/4 | * | Clemson | @ | NC State | |
| 4/9 | * | Virginia | @ | Clemson | 6 pm |
| 4/10 | * | Virginia | @ | Clemson | 3 pm |
| 4/11 | * | Virginia | @ | Clemson | 1 pm |
| 4/13 | College of Charleston | @ | Clemson | 6 pm | |
| 4/16 | * | Clemson | @ | Miami (Fla.) | |
| 4/17 | * | Clemson | @ | Miami (Fla.) | |
| 4/18 | * | Clemson | @ | Miami (Fla.) | |
| 4/20 | Clemson | @ | Georgia | ||
| 4/23 | * | Wake Forest | @ | Clemson | 6 pm |
| 4/24 | * | Wake Forest | @ | Clemson | 3 pm |
| 4/25 | * | Wake Forest | @ | Clemson | 1 pm |
| 4/30 | * | Louisville | @ | Clemson | 6 pm |
| 5/1 | * | Louisville | @ | Clemson | 3 pm |
| 5/2 | * | Louisville | @ | Clemson | 12 pm |
| 5/5 | USC Upstate | @ | Clemson | 6 pm | |
| 5/7 | * | Clemson | @ | Georgia Tech | |
| 5/8 | * | Clemson | @ | Georgia Tech | |
| 5/9 | * | Clemson | @ | Georgia Tech | |
| 5/14 | * | Clemson | @ | Florida State | |
| 5/15 | * | Clemson | @ | Florida State | |
| 5/16 | * | Clemson | @ | Florida State | |
| 5/20 | * | Duke | @ | Clemson | 6 pm |
| 5/21 | * | Duke | @ | Clemson | 6 pm |
| 5/22 | * | Duke | @ | Clemson | 1 pm |
