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| 2/15 | Oklahoma State | @ | UTRGV | 7 pm |
| 2/16 | Oklahoma State | @ | UTRGV | 2 pm |
| 2/17 | Oklahoma State | @ | UTRGV | 12 pm |
| 2/19 | Houston Baptist | @ | UTRGV | 12 pm |
| 2/22 | Portland | @ | UTRGV | 7 pm |
| 2/23 | North Dakota State | @ | UTRGV | 11 am |
| 2/23 | Portland | @ | UTRGV | 3 pm |
| 2/24 | North Dakota State | @ | UTRGV | 3 pm |
| 3/1 | Rhode Island | @ | UTRGV | 7 pm |
| 3/2 | Rhode Island | @ | UTRGV DH | 12 pm |
| 3/3 | Rhode Island | @ | UTRGV | 12 pm |
| 3/5 | UTRGV | @ | Texas | 6:30 pm |
| 3/8 | Massachusetts | @ | UTRGV | 7 pm |
| 3/9 | Massachusetts | @ | UTRGV | 6 pm |
| 3/10 | Massachusetts | @ | UTRGV | 12 pm |
| 3/12 | Texas A&M-Corpus Christi | @ | UTRGV | 7 pm |
| 3/15 | UTRGV | @ | Kansas State | 6 pm |
| 3/16 | UTRGV | @ | Kansas State | 4 pm |
| 3/17 | UTRGV | @ | Kansas State | 1 pm |
| 3/19 | UTRGV | @ | Texas A&M-Corpus Christi | 6 pm |
| 3/22 | * | UTRGV | @ | Sacramento State | 7 pm |
| 3/23 | * | UTRGV | @ | Sacramento State | 3 pm |
| 3/24 | * | UTRGV | @ | Sacramento State | 12 pm |
| 3/26 | UTRGV | @ | TCU | 6:30 pm |
| 3/29 | * | Northern Colorado | @ | UTRGV | 7 pm |
| 3/30 | * | Northern Colorado | @ | UTRGV | 6 pm |
| 3/31 | * | Northern Colorado | @ | UTRGV | 12 pm |
| 4/5 | * | Chicago State | @ | UTRGV | 7 pm |
| 4/6 | * | Chicago State | @ | UTRGV | 6 pm |
| 4/7 | * | Chicago State | @ | UTRGV | 12 pm |
| 4/10 | UTRGV | @ | Houston Baptist | 3 pm |
| 4/12 | * | UTRGV | @ | Grand Canyon | 6:30 pm |
| 4/13 | * | UTRGV | @ | Grand Canyon | 6 pm |
| 4/14 | * | UTRGV | @ | Grand Canyon | 12 pm |
| 4/18 | * | California Baptist | @ | UTRGV | 7 pm |
| 4/19 | * | California Baptist | @ | UTRGV | 7 pm |
| 4/20 | * | California Baptist | @ | UTRGV | 12 pm |
| 4/23 | UTRGV | @ | Incarnate Word | 6:30 pm |
| 4/26 | * | Seattle | @ | UTRGV | 7 pm |
| 4/27 | * | Seattle | @ | UTRGV | 6 pm |
| 4/28 | * | Seattle | @ | UTRGV | 12 pm |
| 4/30 | UTRGV | @ | Texas Tech | 6:30 pm |
| 5/1 | UTRGV | @ | Texas Tech | 2 pm |
| 5/3 | * | UTRGV | @ | New Mexico State | 6 pm |
| 5/4 | * | UTRGV | @ | New Mexico State | 2 pm |
| 5/5 | * | UTRGV | @ | New Mexico State | 12 pm |
| 5/10 | * | UTRGV | @ | CSU Bakersfield | 6 pm |
| 5/11 | * | UTRGV | @ | CSU Bakersfield | 6 pm |
| 5/12 | * | UTRGV | @ | CSU Bakersfield | 12 pm |
| 5/14 | Texas A&M-Corpus Christi | @ | UTRGV | 7 pm |
| 5/16 | * | Utah Valley | @ | UTRGV | 7 pm |
| 5/17 | * | Utah Valley | @ | UTRGV | 7 pm |
| 5/18 | * | Utah Valley | @ | UTRGV | 12 pm |
