| 2/15 | Notre Dame | @ | Arizona State | 6:30 pm | |
| 2/16 | Notre Dame | @ | Arizona State | 6:30 pm | |
| 2/17 | Notre Dame | @ | Arizona State | 12:30 pm | |
| 2/22 | Eastern Michigan | vs. | Notre Dame (San Antonio, Texas) | 3 pm | |
| 2/22 | Incarnate Word | vs. | Notre Dame (San Antonio, Texas) | 7:30 pm | |
| 2/23 | Eastern Michigan | vs. | Notre Dame (San Antonio, Texas) | 2:30 pm | |
| 2/24 | Incarnate Word | vs. | Notre Dame (San Antonio, Texas) | 11:30 am | |
| 3/1 | Notre Dame | @ | Charleston Southern | 1 pm | |
| 3/2 | Ball State | vs. | Notre Dame (Charleston, S.C.) | 11 am | |
| 3/2 | Notre Dame | @ | Charleston Southern | 4 pm | |
| 3/3 | Ball State | vs. | Notre Dame (Charleston, S.C.) | 11 am | |
| 3/8 | * | Notre Dame | @ | Wake Forest | 6 pm |
| 3/9 | * | Notre Dame | @ | Wake Forest | 4 pm |
| 3/10 | * | Notre Dame | @ | Wake Forest | 1 pm |
| 3/12 | Notre Dame | @ | Western Carolina | ||
| 3/15 | * | Notre Dame | @ | Clemson | 6 pm |
| 3/16 | * | Notre Dame | @ | Clemson | 3 pm |
| 3/17 | * | Notre Dame | @ | Clemson | 1 pm |
| 3/22 | * | Florida State | @ | Notre Dame | 6 pm |
| 3/23 | * | Florida State | @ | Notre Dame | 2 pm |
| 3/24 | * | Florida State | @ | Notre Dame | 1 pm |
| 3/26 | Chicago State | @ | Notre Dame | 6 pm | |
| 3/29 | * | Notre Dame | @ | Georgia Tech | |
| 3/30 | * | Notre Dame | @ | Georgia Tech | |
| 3/31 | * | Notre Dame | @ | Georgia Tech | |
| 4/2 | Central Michigan | @ | Notre Dame | 6 pm | |
| 4/3 | Notre Dame | @ | South Bend Cubs (exhibition) | ||
| 4/5 | * | Virginia | @ | Notre Dame | 6 pm |
| 4/6 | * | Virginia | @ | Notre Dame | 2 pm |
| 4/7 | * | Virginia | @ | Notre Dame | 1 pm |
| 4/9 | Michigan State | @ | Notre Dame | 6 pm | |
| 4/10 | Western Michigan | @ | Notre Dame | 6 pm | |
| 4/12 | * | North Carolina | @ | Notre Dame | 6 pm |
| 4/13 | * | North Carolina | @ | Notre Dame | 2 pm |
| 4/14 | * | North Carolina | @ | Notre Dame | 1 pm |
| 4/16 | Northwestern | @ | Notre Dame | 6 pm | |
| 4/19 | * | Notre Dame | @ | Pittsburgh | 6 pm |
| 4/20 | * | Notre Dame | @ | Pittsburgh | 3 pm |
| 4/21 | * | Notre Dame | @ | Pittsburgh | 1 pm |
| 4/23 | Valparaiso | @ | Notre Dame | 6 pm | |
| 4/26 | * | NC State | @ | Notre Dame | 6 pm |
| 4/27 | * | NC State | @ | Notre Dame | 3 pm |
| 4/28 | * | NC State | @ | Notre Dame | 1 pm |
| 4/30 | UIC | @ | Notre Dame | 6 pm | |
| 5/3 | * | Louisville | @ | Notre Dame | 6 pm |
| 5/4 | * | Louisville | @ | Notre Dame | 3 pm |
| 5/5 | * | Louisville | @ | Notre Dame | 1 pm |
| 5/11 | Canisius | @ | Notre Dame DH | 2 pm | |
| 5/12 | Canisius | @ | Notre Dame | 1 pm | |
| 5/14 | Notre Dame | @ | Northwestern | 4:30 pm | |
| 5/16 | * | Notre Dame | @ | Boston College | 7 pm |
| 5/17 | * | Notre Dame | @ | Boston College | 7 pm |
| 5/18 | * | Notre Dame | @ | Boston College | 1 pm |
