| 2/15 | Youngstown State | @ | Mississippi State | 4 pm | |
| 2/16 | Youngstown State | @ | Mississippi State | 2 pm | |
| 2/17 | Youngstown State | @ | Mississippi State | 1 pm | |
| 2/20 | UAB | @ | Mississippi State | 4 pm | |
| 2/22 | Southern Miss | @ | Mississippi State | 4 pm | |
| 2/23 | Southern Miss | @ | Mississippi State | 2 pm | |
| 2/24 | Southern Miss | @ | Mississippi State | 1 pm | |
| 2/26 | Jackson State | @ | Mississippi State | 4 pm | |
| 2/27 | Southeastern Louisiana | @ | Mississippi State | 4 pm | |
| 3/1 | Mississippi State | vs. | Sam Houston State (Frisco, Texas) | 3 pm | |
| 3/2 | Mississippi State | vs. | Texas Tech (Frisco, Texas) | 6 pm | |
| 3/3 | Mississippi State | vs. | Nebraska (Frisco, Texas) | 11 am | |
| 3/5 | East Carolina | @ | Mississippi State | 6:30 pm | |
| 3/6 | UAPB | @ | Mississippi State | 6:30 pm | |
| 3/8 | Maine | @ | Mississippi State | 6:30 pm | |
| 3/9 | Maine | @ | Mississippi State | 3 pm | |
| 3/10 | Maine | @ | Mississippi State | 12 pm | |
| 3/13 | Grambling | @ | Mississippi State | 6:30 pm | |
| 3/15 | * | Mississippi State | @ | Florida | 6:30 pm |
| 3/16 | * | Mississippi State | @ | Florida | 6:30 pm |
| 3/17 | * | Mississippi State | @ | Florida | 1 pm |
| 3/19 | Little Rock | @ | Mississippi State | 6:30 pm | |
| 3/22 | * | Auburn | @ | Mississippi State | 6:30 pm |
| 3/23 | * | Auburn | @ | Mississippi State | 2 pm |
| 3/24 | * | Auburn | @ | Mississippi State | 1 pm |
| 3/26 | Mississippi Valley State | @ | Mississippi State | 6:30 pm | |
| 3/28 | * | LSU | @ | Mississippi State | 6:30 pm |
| 3/29 | * | LSU | @ | Mississippi State | 6:30 pm |
| 3/30 | * | LSU | @ | Mississippi State | 2 pm |
| 4/3 | ULM | @ | Mississippi State | 6:30 pm | |
| 4/5 | * | Mississippi State | @ | Tennessee | 6:30 pm |
| 4/6 | * | Mississippi State | @ | Tennessee | 6 pm |
| 4/7 | * | Mississippi State | @ | Tennessee | 1 pm |
| 4/10 | South Alabama | @ | Mississippi State | 6:30 pm | |
| 4/12 | * | Alabama | @ | Mississippi State | 6:30 pm |
| 4/13 | * | Alabama | @ | Mississippi State | 3 pm |
| 4/14 | * | Alabama | @ | Mississippi State | 1 pm |
| 4/16 | Texas Southern | @ | Mississippi State | 6:30 pm | |
| 4/19 | * | Mississippi State | @ | Arkansas | |
| 4/20 | * | Mississippi State | @ | Arkansas | |
| 4/21 | * | Mississippi State | @ | Arkansas | |
| 4/23 | Mississippi State | vs. | Ole Miss (Pearl, Miss.) | 6 pm | |
| 4/26 | * | Georgia | @ | Mississippi State | 6:30 pm |
| 4/27 | * | Georgia | @ | Mississippi State | 2 pm |
| 4/28 | * | Georgia | @ | Mississippi State | 1 pm |
| 5/2 | * | Mississippi State | @ | Texas A&M | 6:30 pm |
| 5/3 | * | Mississippi State | @ | Texas A&M | 6:30 pm |
| 5/4 | * | Mississippi State | @ | Texas A&M | 1 pm |
| 5/8 | Memphis | @ | Mississippi State | 6:30 pm | |
| 5/10 | * | Mississippi State | @ | Ole Miss | 6:30 pm |
| 5/11 | * | Mississippi State | @ | Ole Miss | 4 pm |
| 5/12 | * | Mississippi State | @ | Ole Miss | 1:30 pm |
| 5/16 | * | South Carolina | @ | Mississippi State | 6:30 pm |
| 5/17 | * | South Carolina | @ | Mississippi State | 6:30 pm |
| 5/18 | * | South Carolina | @ | Mississippi State | 1 pm |
