| 2/15 | South Alabama | @ | Clemson | 4 pm | |
| 2/16 | South Alabama | @ | Clemson | 3 pm | |
| 2/17 | South Alabama | @ | Clemson | 1 pm | |
| 2/19 | Charlotte | @ | Clemson | 4 pm | |
| 2/20 | Tennessee Tech | @ | Clemson | 4 pm | |
| 2/22 | VMI | @ | Clemson | 4 pm | |
| 2/23 | VMI | @ | Clemson | 3 pm | |
| 2/24 | VMI | @ | Clemson | 1 pm | |
| 2/26 | ETSU | @ | Clemson | 4 pm | |
| 3/1 | South Carolina | @ | Clemson | 6 pm | |
| 3/2 | Clemson | vs. | South Carolina (Greenville, S.C.) | ||
| 3/3 | Clemson | @ | South Carolina | ||
| 3/5 | Clemson | @ | Furman | 6 pm | |
| 3/8 | * | North Carolina | @ | Clemson | 6 pm |
| 3/9 | * | North Carolina | @ | Clemson | 3 pm |
| 3/10 | * | North Carolina | @ | Clemson | 1 pm |
| 3/13 | Coastal Carolina | @ | Clemson | 6 pm | |
| 3/15 | * | Notre Dame | @ | Clemson | 6 pm |
| 3/16 | * | Notre Dame | @ | Clemson | 3 pm |
| 3/17 | * | Notre Dame | @ | Clemson | 1 pm |
| 3/19 | College of Charleston | @ | Clemson | 6 pm | |
| 3/20 | Clemson | @ | College of Charleston | 7 pm | |
| 3/22 | * | Clemson | @ | Boston College | 4 pm |
| 3/23 | * | Clemson | @ | Boston College | 2 pm |
| 3/24 | * | Clemson | @ | Boston College | 1 pm |
| 3/26 | Clemson | @ | Charlotte | 7 pm | |
| 3/29 | * | Clemson | @ | Virginia Tech | 6 pm |
| 3/30 | * | Clemson | @ | Virginia Tech | 3 pm |
| 3/31 | * | Clemson | @ | Virginia Tech | 1 pm |
| 4/2 | Georgia | @ | Clemson | 6 pm | |
| 4/5 | * | Louisville | @ | Clemson | 6 pm |
| 4/6 | * | Louisville | @ | Clemson | 5 pm |
| 4/7 | * | Louisville | @ | Clemson | 1 pm |
| 4/9 | Charleston Southern | @ | Clemson | 6 pm | |
| 4/10 | Furman | @ | Clemson | 6 pm | |
| 4/12 | * | Clemson | @ | Florida State | 6 pm |
| 4/13 | * | Clemson | @ | Florida State | 6 pm |
| 4/14 | * | Clemson | @ | Florida State | 1 pm |
| 4/16 | Clemson | @ | Georgia | 7 pm | |
| 4/19 | * | Duke | @ | Clemson | 6 pm |
| 4/20 | * | Duke | @ | Clemson | 3 pm |
| 4/21 | * | Duke | @ | Clemson | 1 pm |
| 4/23 | Winthrop | @ | Clemson | 6 pm | |
| 4/26 | * | Clemson | @ | Georgia Tech | 7 pm |
| 4/27 | * | Clemson | @ | Georgia Tech | 4 pm |
| 4/28 | * | Clemson | @ | Georgia Tech | 1 pm |
| 5/4 | Gardner-Webb | @ | Clemson | 3 pm | |
| 5/5 | Clemson | @ | Gardner-Webb | 2 pm | |
| 5/8 | The Citadel | @ | Clemson | 6 pm | |
| 5/10 | * | Clemson | @ | NC State | 6:30 pm |
| 5/11 | * | Clemson | @ | NC State | 6:30 pm |
| 5/12 | * | Clemson | @ | NC State | 1 pm |
| 5/14 | Clemson | @ | Coastal Carolina | 6 pm | |
| 5/16 | * | Wake Forest | @ | Clemson | 6 pm |
| 5/17 | * | Wake Forest | @ | Clemson | 6 pm |
| 5/18 | * | Wake Forest | @ | Clemson | 1 pm |
